Q: How do I know what type of Provenance Documentation I need to provide?

Please review the Provenance Guidance Document , and if you have questions please contact the hSCRO Administrator at hSCRO@research.uci.edu or contact the hSCRO staff .

Q: Do I have to submit my protocol for review annually?

Yes! The Protocol Renewal Application must be submitted annually. It is recommended that renewals are submitted 8 weeks prior to expiration if the renewal will include amendments that require Full (Convened) hSCRO Committee review. If the renewal does not include any amendments or the amendments are minor (e.g., personnel changes), then submission is recommended 4-6 weeks usually prior to the expiration date.

Question 1

﻿I would like to use adult stem cells in my research. Do I need hSCRO approval?

Accepted Answer

The use of adult tissue specific stem cells, such as hematopoietic cells or mesenchymal cells, does not require UCI hSCRO approval UNLESS such cells have been shown to, or are being induced to differentiate into the three major germ lines.

Question 2

﻿I would like to use a line from the NIH registry (H1, H9, etc.). Do I need hSCRO approval?

Accepted Answer

Yes. For more information on which cell lines require hSCRO review, please visit our Cell Line Provenance Policy webpage.

Question 3

How do I know what type of Provenance Documentation I need to provide?

Accepted Answer

Please review the Provenance Guidance Document, and if you have questions please contact the hSCRO Administrator at hSCRO@research.uci.edu or contact the hSCRO staff.

Question 4

How often does the hSCRO Committee Meet?

Accepted Answer

The Full Committee meets once per month on the first Thursday of the month. The schedule of deadlines and meeting dates can be found on the Committee Calendar
The hSCRO Subcommittee meets weekly.

Question 5

Do I have to submit my protocol for review annually?

Accepted Answer

Yes! The Protocol Renewal Application must be submitted annually. It is recommended that renewals are submitted 8 weeks prior to expiration if the renewal will include amendments that require Full (Convened) hSCRO Committee review. If the renewal does not include any amendments or the amendments are minor (e.g., personnel changes), then submission is recommended 4-6 weeks usually prior to the expiration date.

Question 6

I have an undergraduate working in my lab, but only a few hours a week. Do I have to add them to my protocol?

Accepted Answer

If the student is actively participating in hSCRO covered stem cell / fetal material research you must add them to your protocol.

Question 7

Can I submit an Amendment with a Renewal?

Accepted Answer

Yes, if you are submitting an Amendment requiring Full Committee review, and your protocol expires within the next 90 days, you may also submit a Renew & Amend via the "Renew/Amend" feature in KRP.

Please keep in mind that all Renewals must be submitted as a Renew/Amend in KRP, regardless of if an Amendment is being submitted at the time of Renewal.

That said, submitting a Full Committee Amendment with a Renewal is not recommended. If your hSCRO protocol's expiration is nearing, and the Amendment is Tabled for re-review, the protocol could expire in the time it requires to re-review the Amendment.

Thus, UCI hSCRO recommends submitting the Amendment after the Renewal is approved to avoid lapses in approval.

Please review this webpage to determine if your Amendment would require Full Committee review.

Frequently Asked Questions