Campus News
Stopping chronic pain before it starts
Researchers discovered that after an injury, support cells are temporarily rewired to trigger nerve cells to produce sticky beta-amyloid protein fragments best known for their role in Alzheimer’s disease. In mice, blocking this process shortly after injury prevented pain from becoming persistent without dulling the initial, acute pain response. The findings, published in Science Translational…
Read MoreNew data infrastructure award to help scientific communities build domain-specific platforms for collaborative data science and AI
Irvine, Calif., Aug. 27, 2026 — Researchers at UC Irvine, UCLA and the University of Michigan have received nearly $9 million from the U.S. National Science Foundation to establish a new data infrastructure capability that will help scientific communities across the nation use advanced data science and artificial intelligence tools. The award, called NSF BRIDGE…
Read MoreSocial media: Reading between the lines
UC Irvine researchers analyzed nearly 25,000 heat-related social media posts from across California to examine what factors predict people talking about coping with extreme heat or its effects on daily life. People living in RVs, vans or boats appeared to face greater challenges during extreme heat while being less likely to discuss ways of coping with it.…
Read MoreHow public safety can influence public health
Community-led safety program was associated with increased physical activity at South Los Angeles parks, with the greatest gains among Black visitors. The type of safety intervention was more important than park quality for supporting physical activity The findings suggest that park safety can influence health and health equity. Irvine, Calif., Aug. 26, 2026 — A…
Read MoreLab-grown brain models gain a sense of place
The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it’s organized. Its outer layer, the cerebral cortex, is not one uniform sheet. As the brain develops, it divides into distinct areas that each take on different jobs, from movement and vision…
Read MoreMath and medicine join forces to solve a cancer mystery
Irvine, Calif., Aug. 20, 2026 — Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body’s own immune system to identify and kill cancer cells that had previously escaped elimination. For patients with advanced melanoma – a particularly aggressive form of skin…
Read MoreLifesaving cancer treatment without life-threatening side effects
UC Irvine researchers highlight mitochondrial dysfunction as a promising target for reducing a serious neurological complication of CAR T-cell therapy in cancer patients. The study outlines how existing drugs could be repurposed as safer alternatives to steroids in addressing this complication. The research provides a road map for future clinical evaluation. Irvine, Calif., Aug. 18,…
Read MoreLarge-scale study finds no link between crime and unauthorized immigration
Irvine, Calif., Aug. 11, 2026 — For more than two decades, Charis E. Kubrin has followed the data wherever it leads. As UC Irvine Chancellor’s Professor of Criminology, Law and Society, she has built a career studying one of America’s most politically charged questions: does immigration drive crime? Now, in one of the most geographically…
Read MoreDifferent inflammatory processes tied to the same Alzheimer’s disease-related brain shrinkage and memory loss
Two blood markers of inflammation were associated with different forms of disease markers in the brain. YKL-40 was linked to damage in the brain’s small blood vessels, while GFAP was linked to amyloid buildup. The two routes were associated with a shared pattern involving greater abnormal tau, shrinkage in memory-related brain regions and poorer memory.…
Read MoreFlaunting our faculty
When the University of California, Irvine opened its doors in 1965, it was the youngest campus in the University of California system. Unlike older institutions with generations of established traditions and reputations, UC Irvine began with a blank canvas and an ambitious vision. Over six decades, the campus has matured into one of the nation’s…
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