Untangling the link between depression and gut disease

Among patients with both diagnoses, depression was more often recorded before irritable bowel syndrome, while Crohn’s disease was more often recorded before depression. Ulcerative colitis showed a more mixed pattern. The study analyzed records from more than 630,000 participants in the NIH All of Us Research Program. It confirmed the findings using the University of…

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40 years in the light

40 years in the light

In 1980, Michael Berns sent invitations to every biotech and medical company CEO he could find in Orange County. A UC Irvine cell biologist with a habit of pointing lasers at things nobody else thought to aim them at, Berns wanted them to see the Laser Microbeam Program – a machine he’d spent a year…

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Where Neighbors Guide the Science

This story is a digital preview from the forthcoming fall 2026 edition of UC Irvine Magazine. For Dr. Dan Cooper, caring for individual patients and engaging with the communities where they live go hand in hand. “My interest in community goes way, way back to my time as an undergraduate at UC Santa Cruz in the…

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Department of Energy selects UC Irvine-led, AI-driven geothermal energy project

MAESTRO project experts will use AI to discover and tap into geothermal energy resources safely and economically. Department of Energy-funded initiative was established to improve energy independence and security in the United States. Researchers from UC Berkeley, UC Irvine, UC Riverside, UC San Diego, UC Santa Cruz, four national laboratories (Los Alamos, Lawrence Livermore, Lawrence…

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When it comes to El Niño, it’s best to be prepared

When it comes to El Niño, it's best to be prepared

UC Irvine researchers are tracking a looming El Niño event in the Pacific Ocean. The phenomenon could bring heavy surf, higher-than-usual tides and abundant rainfall, leading to flooding. Public health specialists offer advice on how to protect yourself and your family in the event of extreme weather originating with El Niño. El Niño is a…

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NSF advances plan to build world’s most powerful laser

The National Science Foundation has awarded a round of funding toward a total of $13.7 million to advance the development of the world’s most powerful laser into its final design phase. The NSF Optical Parametric Amplifier Line laser facility, being developed with participation by UC Irvine researchers, will serve as a shared resource by the…

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Efi Foufoula-Georgiou elected to the Royal Academy of Engineering

Irvine, Calif., Sept. 24, 2026 — Efi Foufoula-Georgiou, Distinguished Professor of civil and environmental engineering and Samueli Endowed Chair in engineering at the University of California, Irvine, has been elected an international fellow of the Royal Academy of Engineering. She is among 75 new fellows elected this year to the United Kingdom-based Royal Academy of…

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Stealth tactic makes chemotherapy smarter

Research team designed an experimental prodrug that delivers its toxic, cancer-killing payload inside cells with high immunoproteasome activity, which occurs with certain cancers. Healthy cells are largely unaffected by the masked drug, which is inactive until it enters a cancer cell. In a preclinical model of small cell lung cancer, the treatment significantly reduced tumor…

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​UC Irvine receives $4.2 million NIH award to continue All of Us enrollment

Irvine, Calif. Sept. 16, 2026 — The University of California, Irvine has received a$4.2 million award from the National Institutes of Health to continue enrollment in the All of Us Research Program and to support the study of cardiometabolic health in populations underrepresented in biomedical research. This initiative represents a collaborative NIH effort supported by…

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