Charge of the UCI hSCRO

  1. The Human Stem Cell Research Oversight Committee (hSCRO) assures human stem cell activities are:
    1. In accord with National Academies and California DHS guidelines and ethical guidelines (e.g., Belmont Report, Declaration of Helsinki), and
    2. In compliance with California statute and California Institute for Regenerative Medicine (CIRM) regulations and applicable campus policies and procedures for human stem cell activities.
  2. hSCRO considers the ethical and social issues presented by human stem cell activities.
  3. hSCRO reviews the scientific/scholarly merit of human stem cell activities to assure procedures are consistent with sound research design, the study design can be reasonably expected to answer the proposed questions(s), and the importance of the knowledge expected to result is known.
  4. hSCRO assures that the provenance (origin) of gametes, blastocysts, fetal tissue and the derivation of human stem cells are documented. Documentation should sufficiently establish that procurement of the cell lines complies with standard clinical care consenting procedures and/or human stem cell and research regulations, as applicable.
  5. hSCRO assures documentation of compliance with any required regulatory reviews (e.g., IRB, IACUC and IBC).
  6. hSCRO approves, requires modifications in, or disapproves protocols involving human gametes, embryos and human stem cell activities, subject to the overriding responsibilities of the IRB and IACUC.
  7. hSCRO approves, requires modifications in, or disapproves protocols involving the use of human pluripotent stem cells or the intent to generate subject to the overriding responsibilities of the IRB.

For more information about the hSCRO committee, please see the hSRCO Program Policy & Standard Operating Procedures.

About the UCI hSCRO Committee

The UCI Human Stem Cell Research Oversight (hSCRO) Committee is charged with assuring human stem cell activities are in accordance with California state regulations and UCI policies and procedures.

California Legislature mandated the California Department of Public Health (CDPH) in Health and Safety Code Section 125118 to develop a comprehensive set of guidelines, which would fully address the ethical, legal, and social aspects of stem cell research as well as ensure the systematic monitoring and reporting of human stem cell research activity in California that is not fully funded by Proposition 71 money granted through the California Institute for Regenerative Medicine (CIRM) (Senate Bill 322, Chapter 506, Statutes of 2003; Senate Bill 1260, Chapter 483, Statutes of 2006). Accordingly, when CIRM funding is not involved, the UCI hSCRO follows CDPH regulations.

When CIRM funds are involved, the UCI hSCRO upholds CIRM regulations.

hSCRO Committee Meetings and Deadlines

View the Calendar

Contacting hSCRO

UCI Office of Research hSCRO staff are working 100% remotely. Our business hours are Monday - Friday, 8AM-5PM. All staff are responding to emails and calls as usual. The main phone number — (949) 824-8170 — will send you straight to voicemail. Please be assured that although we are not answering this phone line, all messages are being listened to in real time and forwarded to the appropriate colleague for follow up.

Alternatively, you can email hSCRO staff at hSCRO@research.uci.edu 

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