Human Research Protections

About Human Research Protections (HRP)

HRP manages UCI's human research protections program by providing administrative support to its Institutional Review Boards (IRB), which are responsible for protecting the safety and welfare of human subjects. Federal regulations, state laws, and UC/UCI policy require IRB review and approval before researchers may conduct research involving human subjects.

HRP staff work directly with investigators and their administrative staff to assist them with understanding IRB requirements and the process for submitting research protocols to the IRB. HRP also runs an Education and Quality Improvement Program (EQUIP) to educate and train researchers and conduct quality improvement reviews.

Are You a Participant Looking for Information?

Please check out our page specifically for participants in human subjects research.

Visit the Page

IRB Member Rosters

Find out who serves on IRB Committees

General Information Often Requested by Study Sponsors

Answers to common requests from study sponsors (e.g. FWA and IRB reg. numbers).

Kuali Research Protocols (KRP)

UCI's IRB, sIRB and hSCRO submission and management system.

Go to KRP

KRP User Guide

Contacting the IRB

UCI Office of Research HRP staff are working 100% remotely. Our business hours are Monday -Friday 8AM-5PM. All staff are responding to emails and calls as usual.

The main phone number — (949) 824-8170 — will send you straight to voicemail. Please be assured that although we are not answering this phone line, all messages are being listened to in real time and forwarded to the appropriate colleague for follow up.

You may also email us at IRB@uci.edu

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Tools and Resources

Tutorial Verification Search*

Committee Meetings and Deadlines

Protocol Status and Funding Search*

*Available on campus or Cisco VPN; UCINetID required

IRB Fees

HRP Policy Library

All HRP Policies (Download)

Research Personnel Heat Map

As illustrated by the below Research Personnel Heat Map, only Research Personnel involved in the below activities (illustrated in orange) should be listed in the IRB Application and Protocol Narrative. All other Research Personnel should be tracked in the Study Team Tracking Log. (Note: For more information on IRB COI disclosure requirements, click here).

Role of Research Personnel	Minimal Risk Protocol	Greater Than Minimal Risk Protocol
Access to subject identifiable data including Protected Health Information (PHI) for screening/ determining eligibility	List only the LR and Co-Researcher(s) in the Study Team section in KRP. The LR is required to maintain a Study Team log or something similar to track Research Personnel independently.
Recruiting subjects directly via phone, email or in person
Access to subject identifiable data which may include PHI for data collection purposes
Involvement in the informed consent process (i.e., explaining the study to prospective subject)
Performing research procedures that involve greater than minimal risk		List the LR, Co-Researcher(s) and Research Personnel in the Study Team section in KRP.
Involvement in the interpretation of study data
Finalization of the informed consent process (i.e., able to sign off as the individual obtaining consent)
Has a disclosable financial conflict of interest

HRP NEWS

National Institutes of Health (NIH) Data Sharing Plan Requirements Coming in 2023

Dec 21, 2022

+ UCI Library Resources + UCI Office of Research and Libraries January Webinar (Save the Date) New NIH Requirements Coming: Starting January 25, 2023, the NIH will ...

Mar 9, 2022

View this email in your browser China’s Personal InformationProtection Law (PIPL) China has a new Personal Information Protection Law: the PIPL. The PIPL applies to the ...

Feb 28, 2022

Institutional Review Board Human Research Protections (HRP) – Feb 28, 2022 – Kuali Research Protocols (KRP): Department Chair (DC) or Organized Lead Unit Director (OLUD) ...

Feb 16, 2022

There are 3 types of applications in KRP. Keep this reference on hand when navigating human subject research at UCI. Non-Human Subjects Research (NHSR) Self-Determination Exempt ...

Jan 13, 2022

Kuali Research Protocols (KRP): Department Chair Sign Off Coming March 1, 2022, Department Chair (or their designee) sign off will be required before final IRB approval ...

Dec 6, 2021

Dear Colleagues, We have an updated (still light) agenda for Wednesday’s QRAM below. Looking forward to “seeing” you all! Welcome and Housekeeping IACUC News Property / ...

EQUIP

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