About Human Research Protections (HRP)
HRP manages UCI's human research protections program by providing administrative support to its Institutional Review Boards (IRB), which are responsible for protecting the safety and welfare of human subjects. Federal regulations, state laws, and UC/UCI policy require IRB review and approval before researchers may conduct research involving human subjects.
HRP staff work directly with investigators and their administrative staff to assist them with understanding IRB requirements and the process for submitting research protocols to the IRB. HRP also runs an Education and Quality Improvement Program (EQUIP) to educate and train researchers and conduct quality improvement reviews.
Are You a Participant Looking for Information?
Please check out our page specifically for participants in human subjects research.
HRP Quick Reference Guide
Downloadable guide to help navigate HRP/IRB processes at UCI
IRB Member Rosters
Find out who serves on IRB Committees
General Info for Study Sponsors
Answers to common requests from study sponsors (e.g. FWA and IRB reg. numbers).

Kuali Research Protocols (KRP)
UCI's IRB, sIRB and hSCRO submission and management system.
Tools and Resources
*Available on campus or Cisco VPN; UCINetID required
IRB Protocol Transcription is Complete!
China’s Personal Information Protection Law (PIPL)
KRP: Department Chair (DC) or Organized Lead Unit Director (OLUD) Sign Off
Kuali Research Protocols (KRP): Administrative Determination vs a Protocol for IRB Review
Kuali Research Protocols (KRP): Department Chair Sign Off
UPDATED! Winter QRAM Agenda and Zoom Info
Our Commitment to Quality
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EQUIP
The Education and Quality Improvement Program promotes compliance, champions quality and efficiency in the UCI human research community through education, training, and post-approval monitoring services.