Human Research Protections

About Human Research Protections (HRP)

HRP manages UCI's human research protections program by providing administrative support to its Institutional Review Boards (IRB), which are responsible for protecting the safety and welfare of human subjects. Federal regulations, state laws, and UC/UCI policy require IRB review and approval before researchers may conduct research involving human subjects.

HRP staff work directly with investigators and their administrative staff to assist them with understanding IRB requirements and the process for submitting research protocols to the IRB. HRP also runs an Education and Quality Improvement Program (EQUIP) to educate and train researchers and conduct quality improvement reviews.

Are You a Participant Looking for Information?

Please check out our page specifically for participants in human subjects research.

Visit the Page

IRB Member Rosters

Find out who serves on IRB Committees

General Information Often Requested by Study Sponsors

Answers to common requests from study sponsors (e.g. FWA and IRB reg. numbers).

HRP Fast Facts

Quick Answers to Common Questions

Kuali Research Protocols (KRP)

UCI's IRB, sIRB and hSCRO submission and management system.

Go to KRP

KRP User Guide

Contacting the IRB

UCI Office of Research HRP staff are working 100% remotely. Our business hours are Monday -Friday 8AM-5PM. All staff are responding to emails and calls as usual.

The main phone number — (949) 824-8170 — will send you straight to voicemail. Please be assured that although we are not answering this phone line, all messages are being listened to in real time and forwarded to the appropriate colleague for follow up.

You may also email us at IRB@uci.edu

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Tools and Resources

Tutorial Verification Search*

Committee Meetings and Deadlines

Protocol Status and Funding Search*

*Available on campus or Cisco VPN; UCINetID required

IRB Fees

HRP Policy Library

All HRP Policies (Download)

Research Personnel Heat Map

As illustrated by the below Research Personnel Heat Map, only Research Personnel involved in the below activities (illustrated in orange) should be listed in the IRB Application and Protocol Narrative. All other Research Personnel should be tracked in the Study Team Tracking Log. (Note: For more information on IRB COI disclosure requirements, click here).

Role of Research Personnel	Minimal Risk Protocol	Greater Than Minimal Risk Protocol
Access to subject identifiable data including Protected Health Information (PHI) for screening/ determining eligibility	List only the LR and Co-Researcher(s) in the Study Team section in KRP. The LR is required to maintain a Study Team log or something similar to track Research Personnel independently.
Recruiting subjects directly via phone, email or in person
Access to subject identifiable data which may include PHI for data collection purposes
Involvement in the informed consent process (i.e., explaining the study to prospective subject)
Performing research procedures that involve greater than minimal risk		List the LR, Co-Researcher(s) and Research Personnel in the Study Team section in KRP.
Involvement in the interpretation of study data
Finalization of the informed consent process (i.e., able to sign off as the individual obtaining consent)
Has a disclosable financial conflict of interest

HRP NEWS

New Dropdown Section in KRP User Guide

Sep 20, 2023

Dear Colleagues, The ERA has updated the KRP user guide and added a new dropdown section “Steps to Take to Ensure Receiving the KRP Reminders ...

Sep 8, 2023

Dear Colleagues, This is a reminder for next week’s Quarterly Research Administration Meeting (QRAM). The meeting is scheduled for Wednesday, 09/13, from 10:00AM-11:30AM. Join the ...

Aug 23, 2023

Institutional Review Board Human Research Protections (HRP) HRP Listserv: Important Recruitment Reminders for Researchers! Version August 23, 2023 When recruiting human research subjects, keep ...

Jul 10, 2023

Human Research Protections (HRP) Updated IRB and hSCRO Forms Version July 10, 2023 Updated IRB and hSCRO forms will be released after 5pm on July ...

Jun 15, 2023

Institutional Review Board Human Research Protections (HRP) Using Inclusive, Gender-Neutral Language in the IRB Consent Templates Version June 15, 2023 Effective June 1, 2023, ...

Mar 22, 2023

Hello everyone, Please try this link for this morning’s QRAM: https://zoom.us/j/9498244789 Thank you! Barbara Barbara Inderwiesche, CRA Director, Electronic Research Administration ...

EQUIP

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