Multiple Survival Surgery
Regardless of whether the surgery is categorized as major or minor, multiple survival surgical procedures on a single animal should be evaluated to determine their impact on the animal’s well-being.
Multiple major surgical procedures on a single animal are acceptable only if they are:
- Essential components of a single IACUC-approved research project or protocol;
- Scientifically justified by the investigator; or
- Necessary for clinical reasons.2
Animals should not undergo surgical procedures under more than one protocol, except under a few limited exceptions, such as vendor-performed ovariectomy or neutering performed by campus veterinary staff. All surgeries performed on a single animal must be interrelated components of one project.
Cost savings alone is not a justification for multiple surgical procedures; however, conservation of scarce animal resources may be considered as part of a scientific justification by the IACUC.
One exception to the general rule against multiple survival surgeries is the harvest of oocytes from Xenopus frog species – see guidelines for multiple oocyte harvest.
- 1 9 CFR AWA Chapter 1, Part 1.1
- 2 Guide for the Care and Use of Laboratory Animals, 8th edition, page 30.