Education and Quality Improvement Program (EQUIP) What is EQUIP? In an effort to promote accountability and excellence, UCI HRP has developed the Education and Quality Improvement Program (EQUIP). EQUIP monitors and measures the effectiveness, efficiency and quality of UCI’s human research protection program. The primary purpose of the EQUIP is to provide education, training, and…

Contacting the IRB UCI Office of Research HRP staff are working 100% remotely. Our business hours are Monday-Friday 8AM-5PM. All staff are responding to emails and calls as usual. The main phone number — (949) 824-8170 — will send you straight to voicemail. Please be assured that although we are not answering this phone line,…

For Participants in Human Subject Research Research participants contribute greatly to society through taking part in studies. UCI’s Human Research Protections (HRP) and Institutional Review Board (IRB) exist to ensure the rights and welfare of research participants. Please see the below resources we curated to help answer common questions from participants: Have a Concern or…

Researcher Responsibilities after IRB Review Approval of a research project by the IRB is not the end of the process.  There are a number of post-review requirements that researchers should be mindful of. Among these are reporting of problems or significant changes to the research, maintaining records for both UC/sponsor requirements and for potential audit,…

How to Submit in ZOT IRB ZOT IRB is the submission and management system for UCI’s IRB Effective September 15, 2025, the use of ZOT IRB is required for all IRB submissions or registrations. The IRB will not accept any transactions on the prior IRB system (KRP). For more information about the transition to the…

IRB Submission Process The IRB submission process involves several steps. Select a topic below to learn more: Ethical Guidelines, Regulations and StatutesLead Researcher EligibilityTraining & EducationOther Institutional RequirementsDepartment of Defense Research RequirementsHow to Submit in ZOT IRB

Do You Need IRB Review? All research and other activities, which even in part involve human subjects research, regardless of sponsorship, must be reviewed and approved by the UCI IRB, or registered exempt by the Office of Research (or designee) prior to initiation. TIP! Quick Start Guide Download the PDF Please review the information below…