About Human Research Protections (HRP)

HRP manages UCI's human research protections program by providing administrative support to its Institutional Review Boards (IRB). The IRB is responsible for protecting the safety and welfare of human subjects. Federal regulations, state laws, and UC and UCI policy require IRB review and approval before researchers may conduct research involving human subjects.

HRP staff work directly with investigators and their administrative staff to assist them with understanding IRB requirements and the process for submitting research protocols to the IRB. HRP also runs the Education and Quality Improvement Program (EQUIP) to educate and train researchers and conduct quality improvement reviews.

Are you thinking about participating in human subject research?

Frequently Requested Information

IRB Member Rosters

Access our most recent rosters here.

General Information Often Requested by Study Sponsors

Answers to common requests from study sponsors (e.g. FWA and IRB reg. numbers).

HRP Fast Facts

Quick Answers to Common Questions

CARE-Q Certified

UCI was the pilot site for Care-Q.  Re-accreditation was renewed in 2023.

Kuali Research Protocols (KRP)

UCI's IRB, sIRB and hSCRO submission and management system.

Coming September 2025: 

ZOT IRB + ZOT hSCRO

Vote on the design of the ZOT IRB + ZOT hSCRO logos!

 

Contacting the HRP

Hours: Monday - Friday, 8AM–5PM

Main Phone: (949) 824-8170

Email: IRB@uci.edu

Listserv: Send a blank email to: or-irb-hrp+subscribe@uci.edu

Share Feedback: Suggestion Box

Tools and Resources

 *Available on campus or Cisco VPN; UCINetID required 

HRP NEWS

Upcoming Transition to Huron: Limited Protocol Submissions + Data Migration

Institutional Review Board Human Research Protections (HRP)   Upcoming Transition to Huron: Limited Protocol Submissions + Data Migration June 05, 2025   What is Happening Huron ...
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Minimal Risk Human Subject Research and a Closer Look at Expedited Category 2

Institutional Review Board Human Research Protections (HRP) Minimal Risk Human Subject Research and a Closer Look at Expedited Category 2 May 15, 2025   Federal regulations ...
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Humanitarian Use Devices (HUD)

Institutional Review Board Human Research Protections (HRP) Humanitarian Use Devices (HUD) Version May 2025   A HUD is a medical device intended to benefit patients in ...
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CORRECTION: Updated Compensation for Injury Language

Institutional Review Board Human Research Protections (HRP) Updated Consent Form Templates   April 29, 2025 v2 (correction)   University of California Office of the President (UCOP) ...
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Updated Compensation for Injury Language

Institutional Review Board Human Research Protections (HRP) Updated Consent Forms!   April 29, 2025   On March 5, 2025, the University of California updated Consent language ...
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Early Study Terminations and Suspensions

Institutional Review Board Human Research Protections (HRP) Early Study Terminations and Suspensions   April 28, 2025   Summary:  This document provides guidance and resources for researchers ...
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