Huron IRB + Safety (hSCRO)
The Office of Research is pleased to share that Huron will replace the current IRB and hSCRO e-submission system, Kuali Research Protocols ("KRP").
Our anticipated go-live is scheduled for September 15, 2025.
Currently we are undergoing user testing with our Project Champions Group.
Why are we making this change?
In September 2021, UCI HRP implemented KRP to replace a 20-year-old homegrown system. With the growth of our research enterprise, we determined that a more robust electronic IRB and hSCRO system is needed. After a thorough analysis, we have selected Huron.
Huron is a highly reputable electronic solution. Users characterize Huron as stable, reliable, and efficient. Furthermore, it is widely used by our commercial IRB partners, and research-intensive institutions of higher education, including UCLA, USC, CHLA, and soon, UCSF.
Limited IRB Submissions
In order to transition effectively, limited protocol submissions will begin on August 4, 2025 and run through September 14, 2025. This will allow additional time for HRP to clear their review queue, train on the new system and, importantly, the data migration process.
Exceptions may be made based on how closely the application meets the below criteria. Researchers who qualify will submit through the current process in KRP. To obtain the passcode needed for submission, contact Beverley Alberola or Jessica Sheldon in HRP AFTER August 1, 2025.
The following table illustrates what submissions will and will not be allowed:
| | Not allowed during the limited submission period | Allowed during the limited submission period |
|---|---|---|
| New applications for non-therapeutic research with NO external sponsor (e.g., Dept. funds) |  | |
| Self determination of IRB exemption | | |
| Self determination of non human subject research | | |
| New applications for therapeutic research |  |
|
| New applications with external sponsor support (including pilot projects necessary to secure external sponsor funds) | |
|
| New applications required for a dissertation or thesis | |
|
| Amendments required to ensure subject safety or to enable subject treatment | |
|
| Continuing applications | |
|
| Closing applications | |
Data Migration
Only IRB and hSCRO approved protocols will migrate from KRP to Huron IRB. Un-submitted drafts will be discarded. Not yet approved applications will be discarded. If a protocol is currently under IRB review, work closely with the HRP and the IRB to finalize and approve the application prior to the launch and final data migration – prior to September 15, 2025.
Implementation Timeline
How Can You Help?
We need "Project Champions"!
UCI Colleagues will join in guided tours of Huron IRB + Safety (hSCRO), and periodic meetings through adoption of the system.
Should you have any questions, or if you are interested in being a Project Champion, please reach out to:
Barbara Inderwiesche at barbara.i@uci.edu.