About Human Research Protections (HRP)

HRP manages UCI's human research protections program by providing administrative support to its Institutional Review Boards (IRB), which are responsible for protecting the safety and welfare of human subjects.  Federal regulations, state laws, and UC/UCI policy require IRB review and approval before researchers may conduct research involving human subjects.

HRP staff work directly with investigators and their administrative staff to assist them with understanding IRB requirements and the process for submitting research protocols to the IRB.  HRP also runs an Education and Quality Improvement Program (EQUIP) to educate and train researchers and conduct quality improvement reviews.

Are You a Participant Looking for Information?

Please check out our page specifically for participants in human subjects research.

IRB Member Rosters

Find out who serves on IRB Committees

General Information Often Requested by Study Sponsors

Answers to common requests from study sponsors (e.g. FWA and IRB reg. numbers).

HRP Fast Facts

Quick Answers to Common Questions

CARE-Q Certified

On October 31, 2023 the UCI Institutional Review Board again earned the Consortium for Applied Research Ethics Quality (CARE-Q) Certification.

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Kuali Research Protocols (KRP)

UCI's IRB, sIRB and hSCRO submission and management system.

Contacting the IRB

UCI Office of Research HRP staff work 100% remotely. Our business hours are Monday -Friday 8AM–5PM.

The main phone number — (949) 824-8170 — will send you straight to voicemail. Please be assured that although we are not answering this phone line, all messages are being listened to in real time and forwarded to the appropriate colleague for follow up.

You may also email us at IRB@uci.edu

IRB LISTSERV: To subscribe to HRP News & Announcements, send a blank email to: or-irb-hrp+subscribe@uci.edu

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Tools and Resources

 *Available on campus or Cisco VPN; UCINetID required 


02/21 QRAM Materials Posted

Dear Colleagues,   Thank you for attending our Winter QRAM yesterday! The meeting materials have been posted here: https://research.uci.edu/electronic-research-administration/qram/   Please also share with your areas ...
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HIPAA & Consent Waivers Streamlined

Institutional Review Board (IRB) Human Research Protections (HRP)   HIPAA & Consent Waivers Streamlined Version February 22, 2024 The HIPAA and consent waiver sections of the ...
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Dear Colleagues, Happy New Year! Please save the dates below for the 2024 Quarterly Research Administration Meetings (QRAMs). All meetings are on Wednesdays, 10AM-1130AM. The agenda ...
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Ensuring Safety in the Research Community

Dear Colleagues: Safety is critical to conducting high-quality research, which is why I am writing to highlight three annual safety requirements identified in UCI’s Chemical Hygiene ...
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Updated IRB and hSCRO Forms

Human Research Protections (HRP)   Updated IRB and hSCRO Forms    Version July 10, 2023   Updated IRB and hSCRO forms will be released after 5pm on July ...
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Using Inclusive, Gender-Neutral Language in the IRB Consent Templates.

Institutional Review Board Human Research Protections (HRP)   Using Inclusive, Gender-Neutral Language in the IRB Consent Templates   Version June 15, 2023 Effective June 1, 2023, ...
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